Ok, after you hide from sarc in that huge black box a short movie will
come on. When that's finished you have to kill the 2 thugs/doctors that
are working on their patient. After you kill the two doctors, deactivate
the laser and use your lock pick to unlock the straps which are pinning
Jacobs to the board. After you do that you will here message, the
computer guy or another guy will say to you that there is TONS!  of
security in front of the lab and you'll have to find another way.
Directly in front of the laser about 4 steps away is a garage looking
door. Above it is a security lock system thingy. Stand next to the laser
and, USE should come up. Press circle and you can use it. Aim it at the
security thingamabob and the garage gate will open. There will be
another security thing that you have to shoot too, but this time it will
be next to a little window with a syell door covering it. You have to
use your aiming skills and try and shoot it after that jump through the
little window and you will be out of the lab, therefore the guards will
not KILL YOU!