In the battle with the Domz priest, he will eventually tell you that you are out of control with your soul, and the directional controls will be reversed. A practical way to overcome this is to simply flip the controller upside-down.

Crystal Cargo
If you wanna get some crystals and don't want to go everywhere and get hurt. In the hillys you can go to a ship, (note: it only works if you see a box on the ship) and fire only at the box it will break open and crystals will come out. This is a way you can get crystals without getting hurt. It takes two or three shots to break the
box.